(S) FTY720 Phosphate
(S) FTY720 Phosphate structure
|
Common Name | (S) FTY720 Phosphate | ||
|---|---|---|---|---|
| CAS Number | 402616-26-6 | Molecular Weight | 387.451 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 584.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C19H34NO5P | Melting Point | 184-186ºC | |
| MSDS | USA | Flash Point | 307.1±32.9 °C | |
|
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory.
Nat. Neurosci. 17(7) , 971-80, (2014) FTY720 (fingolimod), an FDA-approved drug for treatment of multiple sclerosis, has beneficial effects in the CNS that are not yet well understood, independent of its effects on immune cell trafficking. We show that FTY720 enters the nucleus, where it is phosp... |
Journals:
More...