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2,5-二氯苯磺酸氯

2,5-二氯苯磺酸氯结构式
2,5-二氯苯磺酸氯结构式
品牌特惠专场
常用名 2,5-二氯苯磺酸氯 英文名 2,5-DICHLOROBENZENESULFONYL CHLORIDE
CAS号 5402-73-3 分子量 245.51100
密度 1.636 g/cm3 沸点 327.6ºC at 760 mmHg
分子式 C6H3Cl3O2S 熔点 36-37 °C(lit.)
MSDS 中文版 美版 闪点 >230 °F
符号 GHS05 GHS07
GHS05, GHS07
信号词 Danger

Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.

Bioorg. Med. Chem. Lett. 16 , 1807, (2006)

A series of novel benzoxazole benzenesulfonamides was synthesized as inhibitors of fructose-1,6-bisphosphatase (FBPase-1). Extensive SAR studies led to a potent inhibitor, 53, with an IC(50) of 0.57microM. Compound 17 exhibited excellent bioavailability and a...