2,5-DICHLOROBENZENESULFONYL CHLORIDE

2,5-DICHLOROBENZENESULFONYL CHLORIDE Structure
2,5-DICHLOROBENZENESULFONYL CHLORIDE structure
Common Name 2,5-DICHLOROBENZENESULFONYL CHLORIDE
CAS Number 5402-73-3 Molecular Weight 245.51100
Density 1.636 g/cm3 Boiling Point 327.6ºC at 760 mmHg
Molecular Formula C6H3Cl3O2S Melting Point 36-37 °C(lit.)
MSDS Chinese USA Flash Point >230 °F
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.

Bioorg. Med. Chem. Lett. 16 , 1807, (2006)

A series of novel benzoxazole benzenesulfonamides was synthesized as inhibitors of fructose-1,6-bisphosphatase (FBPase-1). Extensive SAR studies led to a potent inhibitor, 53, with an IC(50) of 0.57microM. Compound 17 exhibited excellent bioavailability and a...