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4 -溴- 2-碘苯甲胺

4 -溴- 2-碘苯甲胺结构式
4 -溴- 2-碘苯甲胺结构式
品牌特惠专场
常用名 4 -溴- 2-碘苯甲胺 英文名 4-Bromo-2-iodoaniline
CAS号 66416-72-6 分子量 297.919
密度 2.3±0.1 g/cm3 沸点 297.9±30.0 °C at 760 mmHg
分子式 C6H5BrIN 熔点 69-72 °C(lit.)
MSDS 中文版 美版 闪点 134.0±24.6 °C
符号 GHS05 GHS06 GHS09
GHS05, GHS06, GHS09
信号词 Danger

Solid-phase synthesis of 2,3,5-trisubstituted indoles.

Org. Lett. 3 , 3827-3830, (2001)

2,3,5-Trisubstituted indoles are synthesized in three steps starting from resin-bound aniline 2. R1 is introduced by a palladium-mediated coupling of the aryl iodide with terminal alkynes followed by intramolecular cyclization to form the indole core. Acylati...

Palladium-catalyzed synthesis of 2-quinolone derivatives from 2-iodoanilines. Cortese NA, et al.

J. Org. Chem. 43(15) , 2952-2958, (1978)

ON SOME HALOGEN DERIVATIVES OF AROMATIC AMINES AND THEIR ANALYSIS. I. 1. Dains FB, et al.

J. Am. Chem. Soc. 40(6) , 930-936, (1918)

Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.

Bioorg. Med. Chem. Lett. 16(22) , 5907-12, (2006)

Through a comparison of X-ray co-crystallographic data for 1 and 2 in the Chek1 active site, it was hypothesized that the affinity of the indolylquinolinone series (2) for Chek1 kinase would be improved via C6 substitution into the hydrophobic region I (HI) p...