4-Bromo-2-iodoaniline
4-Bromo-2-iodoaniline structure
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Common Name | 4-Bromo-2-iodoaniline | ||
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| CAS Number | 66416-72-6 | Molecular Weight | 297.919 | |
| Density | 2.3±0.1 g/cm3 | Boiling Point | 297.9±30.0 °C at 760 mmHg | |
| Molecular Formula | C6H5BrIN | Melting Point | 69-72 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 134.0±24.6 °C | |
| Symbol |
GHS05, GHS06, GHS09 |
Signal Word | Danger | |
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Solid-phase synthesis of 2,3,5-trisubstituted indoles.
Org. Lett. 3 , 3827-3830, (2001) 2,3,5-Trisubstituted indoles are synthesized in three steps starting from resin-bound aniline 2. R1 is introduced by a palladium-mediated coupling of the aryl iodide with terminal alkynes followed by intramolecular cyclization to form the indole core. Acylati... |
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Palladium-catalyzed synthesis of 2-quinolone derivatives from 2-iodoanilines. Cortese NA, et al.
J. Org. Chem. 43(15) , 2952-2958, (1978)
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ON SOME HALOGEN DERIVATIVES OF AROMATIC AMINES AND THEIR ANALYSIS. I. 1. Dains FB, et al.
J. Am. Chem. Soc. 40(6) , 930-936, (1918)
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Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.
Bioorg. Med. Chem. Lett. 16(22) , 5907-12, (2006) Through a comparison of X-ray co-crystallographic data for 1 and 2 in the Chek1 active site, it was hypothesized that the affinity of the indolylquinolinone series (2) for Chek1 kinase would be improved via C6 substitution into the hydrophobic region I (HI) p... |