戈米辛A
戈米辛A结构式
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常用名 | 戈米辛A | 英文名 | Gomisin A |
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| CAS号 | 58546-54-6 | 分子量 | 416.464 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 579.7±50.0 °C at 760 mmHg | |
| 分子式 | C23H28O7 | 熔点 | 88.5°C | |
| MSDS | 中文版 美版 | 闪点 | 304.4±30.1 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Gomisin A inhibits lipopolysaccharide-induced inflammatory responses in N9 microglia via blocking the NF-κB/MAPKs pathway.
Food Chem. Toxicol. 63 , 119-27, (2014) Gomisin A, one of the major dibenzocyclooctadiene lignans isolated from Schisandra chinensis Baill., has proved to possess a variety of pharmacological effects. The aim of the present study was to investigate the anti-inflammatory and neuroprotective effects ... |
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Gomisin A enhances tumor necrosis factor-α-induced G1 cell cycle arrest via signal transducer and activator of transcription 1-mediated phosphorylation of retinoblastoma protein.
Biol. Pharm. Bull. 35(11) , 1997-2003, (2012) Gomisin A, a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra chinensis, has been reported as an anti-cancer substance. In this study, we investigated the effects of gomisin A on cancer cell proliferation and cell cycle arrest in HeLa cells.... |
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Antihypertensive effect of gomisin A from Schisandra chinensis on angiotensin II-induced hypertension via preservation of nitric oxide bioavailability.
Hypertens. Res. 35(9) , 928-34, (2012) Gomisin A (GA) is a small molecular weight lignan present in Schisandra chinensis, and has been demonstrated to have vasodilatory activity. In the present study, we investigated the effect of GA on blood pressure (BP) in angiotensin II (Ang II)-induced hypert... |