油酸
油酸结构式
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常用名 | 油酸 | 英文名 | oleic acid |
|---|---|---|---|---|
| CAS号 | 112-80-1 | 分子量 | 282.461 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 360.0±0.0 °C at 760 mmHg | |
| 分子式 | C18H34O2 | 熔点 | 13-14 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 270.1±14.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Differential expression of efflux pump genes of Mycobacterium tuberculosis in response to varied subinhibitory concentrations of antituberculosis agents.
Tuberculosis (Edinb.) 95(2) , 155-61, (2015) Several reports have elaborated on the role of efflux pumps in drug resistance in Mycobacterium tuberculosis by analysing the mRNA expression profiles. However, there is no uniformity in the subinhibitory concentrations of drugs chosen in these studies. Some ... |
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Decreased lipogenesis in white adipose tissue contributes to the resistance to high fat diet-induced obesity in phosphatidylethanolamine N-methyltransferase-deficient mice.
Biochim. Biophys. Acta 1851(2) , 152-62, (2015) Mice lacking phosphatidylethanolamine N-methyltransferase (PEMT, Pemt(-/-) mice) are resistant to high-fat diet (HFD)-induced obesity (DIO) but develop non-alcoholic steatohepatitis. PEMT expression is strongly induced during differentiation of 3T3-L1 adipocy... |
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Exploring the impact of drug properties on the extent of intestinal lymphatic transport - in vitro and in vivo studies.
Pharm. Res. 32(5) , 1817-29, (2015) Intestinal lymphatic transport of specific lipophilic drugs offers therapeutic advantages and maximises oral bioavailability. The aims of this study were; to compare intestinal lymphatic transport of a range of drugs and to investigate the influence of cyclos... |
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Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol.
J. Physiol. 593(8) , 2097-109, (2015) Sensing of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and behavioural responses. However, the exact physiological pathways linking intestinal fat sensing to food intake and the activation of brain circuits remai... |
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Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification.
Biochem. J. 465(1) , 79-87, (2015) Aldehyde dehydrogenases (ALDHs) catalyse the conversion of toxic aldehydes into non-toxic carboxylic acids. Of the 21 ALDHs in mice, it is the ALDH3 family members (ALDH3A1, ALDH3A2, ALDH3B1, ALDH3B2 and ALDH3B3) that are responsible for the removal of lipid-... |
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Aerosol Mycobacterium tuberculosis infection causes rapid loss of diversity in gut microbiota.
PLoS ONE 9(5) , e97048, (2014) Mycobacterium tuberculosis is an important human pathogen, and yet diagnosis remains challenging. Little research has focused on the impact of M. tuberculosis on the gut microbiota, despite the significant immunological and homeostatic functions of the gastro... |
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Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin.
AAPS J. 16(4) , 875-83, (2014) The effect of food intake on the release and degradation of peptide drugs from solid lipid particles is unknown and was therefore investigated in vitro using different fed state media in a lipolysis model. Desmopressin was used as a model peptide and incorpor... |
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A new magnetic nanocapsule containing 5-fluorouracil: in vivo drug release, anti-tumor, and pro-apoptotic effects on CT26 cells allograft model.
J. Biomater. Appl. 29(4) , 548-56, (2014) The purpose of this study was to create an optimized method for preparation of 5-fluorouracil-loaded magnetic poly lactic-co-glycolic acid nanocapsules and to investigate its potential as multifunctional carriers to deliver therapeutic agents for tumor-target... |
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Phenotypic characterization of a novel double knockout PknI/DacB2 from Mycobacterium tuberculosis.
Microbiol. Res. 170 , 255-62, (2014) Serine/threonine protein kinases play a major role in peptidoglycan biosynthesis in Mycobacterium tuberculosis. To explore the mechanism in detail, in the present study, we have constructed a double knockout (DKO) strain lacking pknI and dacB2 in M. tuberculo... |
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The conserved hypothetical protein Rv0574c is required for cell wall integrity, stress tolerance, and virulence of Mycobacterium tuberculosis.
Infect. Immun. 83(1) , 120-9, (2014) The virulence of Mycobacterium tuberculosis is intimately related to its distinctive cell wall. The biological significance of poly-α-L-glutamine (PLG), a component in the cell wall of virulent mycobacteria, has not been explored adequately. The focus of this... |