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双甘肽

双甘肽结构式
双甘肽结构式
品牌特惠专场
常用名 双甘肽 英文名 H-Gly-Gly-OH
CAS号 556-50-3 分子量 132.118
密度 1.3±0.1 g/cm3 沸点 453.2±30.0 °C at 760 mmHg
分子式 C4H8N2O3 熔点 220-240 °C (dec.)
MSDS 中文版 美版 闪点 227.9±24.6 °C
符号 GHS07
GHS07
信号词 Warning

Abiogenic Syntheses of Lipoamino Acids and Lipopeptides and their Prebiotic Significance.

Orig. Life Evol. Biosph. 45 , 427-37, (2015)

Researchers have formed peptide bonds under a variety of presumed prebiotic conditions. Here it is proposed that these same conditions would have also formed amide bonds between fatty acids and amino acids, producing phosphate-free amphipathic lipoamino acids...

Recurrence of carbamoyl phosphate synthetase 1 (CPS1) deficiency in Turkish patients: characterization of a founder mutation by use of recombinant CPS1 from insect cells expression.

Mol. Genet. Metab. 113(4) , 267-73, (2014)

Carbamoyl phosphate synthetase 1 (CPS1) deficiency due to CPS1 mutations is a rare autosomal-recessive urea cycle disorder causing hyperammonemia that can lead to death or severe neurological impairment. CPS1 catalyzes carbamoyl phosphate formation from ammon...

Inhibition of calcium-calmodulin complex formation by vasorelaxant basic dipeptides demonstrated by in vitro and in silico analyses.

Biochim. Biophys. Acta 1840(10) , 3073-8, (2014)

Tryptophan-histidine (Trp-His) was found to suppress the activity of the Ca²⁺/calmodulin (CaM)-dependent protein kinases II (CaMKII), which requires the Ca²⁺-CaM complex for an initial activation. In this study, we attempted to clarify whether Trp-His inhibit...

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid anal...

Arabidopsis HFR1 is a potential nuclear substrate regulated by the Xanthomonas type III effector XopD(Xcc8004).

PLoS ONE 10(2) , e0117067, (2015)

XopDXcc8004, a type III effector of Xanthomonas campestris pv. campestris (Xcc) 8004, is considered a shorter version of the XopD, which lacks the N-terminal domain. To understand the functions of XopDXcc8004, in planta, a transgenic approach combined with in...

Mapping the Interaction of B Cell Leukemia 3 (BCL-3) and Nuclear Factor κB (NF-κB) p50 Identifies a BCL-3-mimetic Anti-inflammatory Peptide.

J. Biol. Chem. 290 , 15687-96, (2015)

The NF-κB transcriptional response is tightly regulated by a number of processes including the phosphorylation, ubiquitination, and subsequent proteasomal degradation of NF-κB subunits. The IκB family protein BCL-3 stabilizes a NF-κB p50 homodimer·DNA complex...

Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.

J. Exp. Med. 212 , 1529-49, (2015)

Inactivating mutations of the NF-κB essential modulator (NEMO), a key component of NF-κB signaling, cause the genetic disease incontinentia pigmenti (IP). This leads to severe neurological symptoms, but the mechanisms underlying brain involvement were unclear...

Validation of the 2nd Generation Proteasome Inhibitor Oprozomib for Local Therapy of Pulmonary Fibrosis.

PLoS ONE 10 , e0136188, (2015)

Proteasome inhibition has been shown to prevent development of fibrosis in several organs including the lung. However, effects of proteasome inhibitors on lung fibrosis are controversial and cytotoxic side effects of the overall inhibition of proteasomal prot...

Umami-bitter interactions: the suppression of bitterness by umami peptides via human bitter taste receptor.

Biochem. Biophys. Res. Commun. 456(2) , 586-90, (2015)

Taste-taste interactions often showed in human psychophysical studies. Considering that each tastant in foodstuffs individually stimulates its responsible gustatory systems to elicit relevant taste modalities, taste-taste interaction should be performed in ta...

Determination of the isoflavone composition and estrogenic activity of commercial dietary supplements based on soy or red clover.

Food Funct. 6 , 2017-25, (2015)

Dietary supplements high in isolated isoflavones are commercially available for human consumption primarily to alleviate menopausal symptoms in women. The isoflavone composition, quantity and importantly their estrogenic potency are poorly standardised and ca...