盐酸决奈达隆
盐酸决奈达隆结构式
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常用名 | 盐酸决奈达隆 | 英文名 | Dronedarone hydrochloride |
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| CAS号 | 141625-93-6 | 分子量 | 593.217 | |
| 密度 | N/A | 沸点 | 683.9ºC at 760mmHg | |
| 分子式 | C31H45ClN2O5S | 熔点 | NA (low-melting) | |
| MSDS | 中文版 美版 | 闪点 | 367.4ºC |
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Use of In Vitro Morphogenesis of Mouse Embryoid Bodies to Assess Developmental Toxicity of Therapeutic Drugs Contraindicated in Pregnancy.
Toxicol. Sci. 149 , 15-30, (2016) In utero exposure to certain chemicals can impair embryo development, causing embryonic death, growth retardation, or severe birth defects. Establishment of effective in vitro tests is crucial for identifying developmental toxicants and for reducing the finan... |
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Inactivation of Human Cytochrome P450 3A4 and 3A5 by Dronedarone and N-Desbutyl Dronedarone.
Mol. Pharmacol. 89 , 1-13, (2015) Dronedarone is an antiarrhythmic agent approved in 2009 for the treatment of atrial fibrillation. An in-house preliminary study demonstrated that dronedarone inhibits cytochrome P450 (CYP) 3A4 and 3A5 in a time-dependent manner. This study aimed to investigat... |
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