Dronedarone hydrochloride
Dronedarone hydrochloride structure
|
Common Name | Dronedarone hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 141625-93-6 | Molecular Weight | 593.217 | |
| Density | N/A | Boiling Point | 683.9ºC at 760mmHg | |
| Molecular Formula | C31H45ClN2O5S | Melting Point | NA (low-melting) | |
| MSDS | Chinese USA | Flash Point | 367.4ºC | |
|
Use of In Vitro Morphogenesis of Mouse Embryoid Bodies to Assess Developmental Toxicity of Therapeutic Drugs Contraindicated in Pregnancy.
Toxicol. Sci. 149 , 15-30, (2016) In utero exposure to certain chemicals can impair embryo development, causing embryonic death, growth retardation, or severe birth defects. Establishment of effective in vitro tests is crucial for identifying developmental toxicants and for reducing the finan... |
|
|
Inactivation of Human Cytochrome P450 3A4 and 3A5 by Dronedarone and N-Desbutyl Dronedarone.
Mol. Pharmacol. 89 , 1-13, (2015) Dronedarone is an antiarrhythmic agent approved in 2009 for the treatment of atrial fibrillation. An in-house preliminary study demonstrated that dronedarone inhibits cytochrome P450 (CYP) 3A4 and 3A5 in a time-dependent manner. This study aimed to investigat... |
Journals:
More...