鸟嘌呤
鸟嘌呤结构式
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常用名 | 鸟嘌呤 | 英文名 | Guanine |
|---|---|---|---|---|
| CAS号 | 73-40-5 | 分子量 | 151.126 | |
| 密度 | 2.2±0.1 g/cm3 | 沸点 | 561.5±42.0 °C at 760 mmHg | |
| 分子式 | C5H5N5O | 熔点 | >300 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 293.4±27.9 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile.
J. Bacteriol. 197(5) , 819-32, (2015) Clostridium difficile is an anaerobic Gram-positive bacterium that causes intestinal infections with symptoms ranging from mild diarrhea to fulminant colitis. Cyclic diguanosine monophosphate (c-di-GMP) is a bacterial second messenger that typically regulates... |
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Electrochemical tuning of oxygen-containing groups on graphene oxides: towards control of the performance for the analysis of biomarkers.
Phys. Chem. Chem. Phys. 16(24) , 12178-82, (2014) Graphene materials are very popular in the field of biosensing owing to their distinctive characteristics. However, oxygen-containing groups are known to exist intrinsically in graphene-related materials. These groups influence the electrochemical properties ... |
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Development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) aptasensor for direct detection of DNA hybridization.
Phys. Chem. Chem. Phys. 17 , 21356-63, (2015) Rapid detection of disease biomarkers at the patient point-of-care is essential to timely and effective treatment. The research described herein focuses on the development of an electrochemical surface-enhanced Raman spectroscopy (EC-SERS) DNA aptasensor capa... |
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Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme.
J. Biol. Chem. 290 , 12879-98, (2015) The Ras family small GTPases regulate multiple cellular processes, including cell growth, survival, movement, and gene expression, and are intimately involved in cancer pathogenesis. Activation of these small GTPases is catalyzed by a special class of enzymes... |
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Polyphenol extract from evening primrose pomace alleviates experimental colitis after intracolonic and oral administration in mice.
Naunyn Schmiedebergs Arch. Pharmacol. 387(11) , 1069-78, (2014) Oenothera paradoxa (EP) preparations are commonly used in folk medicine to treat skin diseases, neuralgia, and gastrointestinal (GI) disorders. Several reports suggested that EP preparations exhibit potent anti-inflammatory and antioxidant activities both in ... |
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Comprehensive quantitative analysis of purines and pyrimidines in the human malaria parasite using ion-pairing ultra-performance liquid chromatography-mass spectrometry.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 127-33, (2014) Targeted metabolite profiling has aided in the understanding of a variety of biological processes in the malaria parasite as well as in drug discovery. A fast and sensitive analytical method, based on ion-pairing reversed phase ultra-high performance liquid c... |
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Proteomics analysis of EV71-infected cells reveals the involvement of host protein NEDD4L in EV71 replication.
J. Proteome Res. 14(4) , 1818-30, (2015) Enterovirus 71 (EV71) is a human enterovirus that has seriously affected the Asia-Pacific area for the past two decades. EV71 infection can result in mild hand-foot-and-mouth disease and herpangina and may occasionally lead to severe neurological complication... |
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Simultaneous quantification of purine and pyrimidine bases, nucleosides and their degradation products in bovine blood plasma by high performance liquid chromatography tandem mass spectrometry.
J. Chromatogr. A. 1356 , 197-210, (2014) Improved nitrogen utilization in cattle is important in order to secure a sustainable cattle production. As purines and pyrimidines (PP) constitute an appreciable part of rumen nitrogen, an improved understanding of the absorption and intermediary metabolism ... |
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Origin of life. From hell on Earth, life's building blocks.
Science 346(6215) , 1279, (2014)
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Expression of O(6)-methylguanine-DNA methyltransferase causes lomustine resistance in canine lymphoma cells.
Can. J. Vet. Res. 79 , 201-9, (2015) The DNA repair protein O (6)-methylguanine-DNA methyltransferase (MGMT) causes resistance to nitrosoureas in various human cancers. In this study, we analyzed the correlation between canine lymphomas and MGMT in vitro. Two of five canine lymphoma cell lines r... |