前往化源商城

(S)-(+)-α-甲氧基苯乙酸

(S)-(+)-α-甲氧基苯乙酸结构式
(S)-(+)-α-甲氧基苯乙酸结构式
品牌特惠专场
常用名 (S)-(+)-α-甲氧基苯乙酸 英文名 Guaiacol acetate
CAS号 26164-26-1 分子量 166.174
密度 1.2±0.1 g/cm3 沸点 283.8±0.0 °C at 760 mmHg
分子式 C9H10O3 熔点 64-66 °C(lit.)
MSDS 中文版 美版 闪点 116.1±15.3 °C
符号 GHS07
GHS07
信号词 Warning

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.

Bioorg. Med. Chem. 22(17) , 4968-97, (2014)

TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m...