Guaiacol acetate structure
|
Common Name | Guaiacol acetate | ||
|---|---|---|---|---|
| CAS Number | 26164-26-1 | Molecular Weight | 166.174 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 283.8±0.0 °C at 760 mmHg | |
| Molecular Formula | C9H10O3 | Melting Point | 64-66 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 116.1±15.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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