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姥鲛烷

姥鲛烷结构式
姥鲛烷结构式
品牌特惠专场
常用名 姥鲛烷 英文名 Pristane
CAS号 1921-70-6 分子量 268.521
密度 0.8±0.1 g/cm3 沸点 296.0±0.0 °C at 760 mmHg
分子式 C19H40 熔点 -99ºC
MSDS 中文版 美版 闪点 140.7±12.3 °C
符号 GHS07
GHS07
信号词 Warning

No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.

PLoS ONE 9(12) , e115474, (2014)

Apart from their role in the immune defence against pathogens evidence of a role of antimicrobial peptides (AMPs) in autoimmune diseases has accumulated in the past years. The aim of this project was to examine the functional impact of the human cathelicidin ...

IL-17 promotes murine lupus.

J. Immunol. 193(2) , 540-3, (2014)

The proinflammatory activity of IL-17-producing Th17 cells has been associated with the pathogenesis of several autoimmune diseases. In this article, we provide direct evidence for a role of IL-17 in the pathogenesis of systemic lupus erythematosus (SLE). The...

Positional identification of RT1-B (HLA-DQ) as susceptibility locus for autoimmune arthritis.

J. Immunol. 194(6) , 2539-50, (2015)

Rheumatoid arthritis (RA) is associated with amino acid variants in multiple MHC molecules. The association to MHC class II (MHC-II) has been studied in several animal models of RA. In most cases these models depend on T cells restricted to a single immunodom...

Preparation of human tau exon-2- and -10-specific monoclonal antibodies for the recognition of brain tau proteins in various mammals.

Int. J. Mol. Med. 36 , 455-62, (2015)

The aggregations of tau protein in brain tissue have been described in a large number of neurodegenerative diseases; however, due to the lack of tau isoform- or exon-specific antibodies, the exact situations under which various brain tau isoforms can be found...

Bmal1 is an essential regulator for circadian cytosolic Ca²⁺ rhythms in suprachiasmatic nucleus neurons.

J. Neurosci. 34(36) , 12029-38, (2014)

The hypothalamic suprachiasmatic nucleus (SCN) plays a pivotal role in the mammalian circadian clock system. Bmal1 is a clock gene that drives transcriptional-translational feedback loops (TTFLs) for itself and other genes, and is expressed in nearly all SCN ...

Differentiating the roles of photooxidation and biodegradation in the weathering of Light Louisiana Sweet crude oil in surface water from the Deepwater Horizon site.

Mar. Pollut. Bull. 95 , 265-72, (2015)

We determined the contributions of photooxidation and biodegradation to the weathering of Light Louisiana Sweet crude oil by incubating surface water from the Deepwater Horizon site under natural sunlight and temperature conditions. N-alkane biodegradation ra...

A monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (CEA) and restricts CEA expressing tumor growth.

J. Immunother. 37(8) , 394-406, (2014)

Carcinoembryonic antigen (CEA) is one of the promising tumor antigens mainly associated with carcinoma of the colon, lung, breast, etc. and received wide attention for cancer immunotherapy. Neem leaf glycoprotein (NLGP), an effective immunomodulator, is able ...

Nanoscale intimacy in bifunctional catalysts for selective conversion of hydrocarbons.

Nature 528 , 245-8, (2015)

The ability to control nanoscale features precisely is increasingly being exploited to develop and improve monofunctional catalysts. Striking effects might also be expected in the case of bifunctional catalysts, which are important in the hydrocracking of fos...

Dual B cell immunotherapy is superior to individual anti-CD20 depletion or BAFF blockade in murine models of spontaneous or accelerated lupus.

Arthritis Rheumatology 67(1) , 215-24, (2014)

To determine whether a combination of B cell depletion and BAFF blockade is more effective than monotherapy in treating models of spontaneous or accelerated systemic lupus erythematosus (SLE) in (NZB × NZW)F1 mice.Clinical parameters such as disease progressi...

Suppression of Autoimmunity and Renal Disease in Pristane-Induced Lupus by Myeloperoxidase.

Arthritis Rheumatology 67 , 1868-80, (2015)

Myeloperoxidase (MPO) locally contributes to organ damage in various chronic inflammatory conditions by generating reactive intermediates. The contribution of MPO in the development of experimental lupus is unknown. The aim of this study was to define the rol...