Pristane

Modify Date: 2024-01-02 18:00:57

Pristane structure	Common Name	Pristane
	CAS Number	1921-70-6	Molecular Weight	268.521
	Density	0.8±0.1 g/cm3	Boiling Point	296.0±0.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₄₀	Melting Point	-99ºC
	MSDS	Chinese USA	Flash Point	140.7±12.3 °C
	Symbol	GHS07	Signal Word	Warning

Use of Pristane

Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2].

Name	pristane
Synonym	More Synonyms

Description	Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Pristane activates CD4+ αβT cells that are MHC class II restricted and arthritogenic[1].
In Vivo	Pristane activates CD4+ alpha beta T cells that are MHC class II restricted and arthritogenic in vivo[2]. Animal Model: Naive recipient rats (DA)[2] Dosage: 500 μL of Pristane oil Administration: Intradermal injection Result: Both CD4+, CD8+ αβT cells and B cells significantly expand in draining lymph nodes until day 6 after injection, whereafter the CD4+ αβT cells continue to expand until day 12 after injection.
References	[1]. J J Turner, et al. Krypton Fluoride: Preparation by the Matrix Isolation Technique. Science. 1963 May 31;140(3570):974-5. [2]. Jens Holmberg,et al. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol. 2006 Jan 15;176(2):1172-9.

Density	0.8±0.1 g/cm3
Boiling Point	296.0±0.0 °C at 760 mmHg
Melting Point	-99ºC
Molecular Formula	C₁₉H₄₀
Molecular Weight	268.521
Flash Point	140.7±12.3 °C
Exact Mass	268.312988
LogP	10.11
Appearance of Characters	liquid \| Clear colorless
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.436
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

Pristane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RZ1880000

CHEMICAL NAME :: Pentadecane, 2,6,10,14-tetramethyl-

CAS REGISTRY NUMBER :: 1921-70-6

BEILSTEIN REFERENCE NO. :: 1720538

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C19-H40

MOLECULAR WEIGHT :: 268.59

WISWESSER LINE NOTATION :: 1Y1&3Y1&3Y1&3Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human - man

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 47 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,579,1980

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg/26W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Blood - tumors

REFERENCE :: NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 222,994,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1465 No. of Facilities: 66 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 19599 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RZ1880000
HS Code	2901100000

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HS Code	2901100000
Summary	2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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Norphytan

2,6,10,10-Tetramethylpentadecane

2,4-DIPHENYL-6-(4'-METHOXYPHENYL)PYRYLIUM PERCHLORATE

2,6,10,14-Tetramethylpentadecane

Pristane

Pristan

Pentadecane, 2,6,10,14-tetramethyl-

MFCD00008952

EINECS 217-650-8

Norphytane

Bute hydrocarbon

UNII-26HZV48DT1

Pentadecane,2,6,10,14-tetramethyl

2,6,10,14-tetramethyl pentadecane

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pristane
Price: ￥658.0/5ml
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pristane
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pentadecane,2,6,10,14-tetramethyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: pristane
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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