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Related CAS#:
1921-70-6 16416-35-6
3892-00-0

1921-70-6

1921-70-6 structure
1921-70-6 structure
  • Name: Pristane
  • Chemical Name: pristane
  • CAS Number: 1921-70-6
  • Molecular Formula: C19H40
  • Molecular Weight: 268.521
  • Catalog: Chemical reagent Organic reagent Alkane
  • Create Date: 2018-08-10 08:55:25
  • Modify Date: 2024-01-02 18:00:57
  • Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2].
Name pristane
Synonyms Norphytan
2,6,10,10-Tetramethylpentadecane
2,4-DIPHENYL-6-(4'-METHOXYPHENYL)PYRYLIUM PERCHLORATE
2,6,10,14-Tetramethylpentadecane
Pristane
Pristan
Pentadecane, 2,6,10,14-tetramethyl-
MFCD00008952
EINECS 217-650-8
Norphytane
Bute hydrocarbon
UNII-26HZV48DT1
Pentadecane,2,6,10,14-tetramethyl
2,6,10,14-tetramethyl pentadecane
Description Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2].
Related Catalog
In Vitro Pristane activates CD4+ αβT cells that are MHC class II restricted and arthritogenic[1].
In Vivo Pristane activates CD4+ alpha beta T cells that are MHC class II restricted and arthritogenic in vivo[2]. Animal Model: Naive recipient rats (DA)[2] Dosage: 500 μL of Pristane oil Administration: Intradermal injection Result: Both CD4+, CD8+ αβT cells and B cells significantly expand in draining lymph nodes until day 6 after injection, whereafter the CD4+ αβT cells continue to expand until day 12 after injection.
References

[1]. J J Turner, et al. Krypton Fluoride: Preparation by the Matrix Isolation Technique. Science. 1963 May 31;140(3570):974-5.

[2]. Jens Holmberg,et al. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol. 2006 Jan 15;176(2):1172-9.
Density 0.8±0.1 g/cm3
Boiling Point 296.0±0.0 °C at 760 mmHg
Melting Point -99ºC
Molecular Formula C19H40
Molecular Weight 268.521
Flash Point 140.7±12.3 °C
Exact Mass 268.312988
LogP 10.11
Appearance liquid | Clear colorless
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.436
Stability Stable. Combustible. Incompatible with strong oxidizing agents.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RZ1880000
CHEMICAL NAME :
Pentadecane, 2,6,10,14-tetramethyl-
CAS REGISTRY NUMBER :
1921-70-6
BEILSTEIN REFERENCE NO. :
1720538
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C19-H40
MOLECULAR WEIGHT :
268.59
WISWESSER LINE NOTATION :
1Y1&3Y1&3Y1&3Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human - man
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Mammal - pig
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
47 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - tumors
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 40,579,1980
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
60 mg/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Blood - tumors
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 222,994,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1465 No. of Facilities: 66 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 19599 (estimated)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi
Risk Phrases R36/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS RZ1880000
HS Code 2901100000
925694-14-0 structure

925694-14-0

~%

1921-70-6 structure

1921-70-6
Literature: Organic Letters, , vol. 9, # 2 p. 299 - 302
925694-12-8 structure

925694-12-8

~%

1921-70-6 structure

1921-70-6
Literature: Organic Letters, , vol. 9, # 2 p. 299 - 302
502-67-0 structure

502-67-0

~%

1921-70-6 structure

1921-70-6
Literature: Organic Letters, , vol. 9, # 2 p. 299 - 302
253686-88-3 structure

253686-88-3

~%

1921-70-6 structure

1921-70-6
Literature: Chemistry Letters, , # 3 p. 206 - 207
21980-66-5 structure

21980-66-5

~%

1921-70-6 structure

1921-70-6
Literature: Acta Chemica Scandinavica (1947-1973), , vol. 3, p. 942
960359-09-5 structure

960359-09-5

~%

1921-70-6 structure

1921-70-6
Literature: Tanaka, Katsunori; Fukase, Koichi Organic Process Research and Development, 2009 , vol. 13, # 5 p. 983 - 990
502-69-2 structure

502-69-2

~%

1921-70-6 structure

1921-70-6
Literature: Acta Chemica Scandinavica (1947-1973), , vol. 3, p. 942
645-72-7 structure

645-72-7

~9%

1921-70-6 structure

1921-70-6

2140-82-1 structure

2140-82-1
638-36-8 structure

638-36-8
Detail
Literature: Chemistry Letters, , # 3 p. 206 - 207
2140-82-1 structure

2140-82-1

~%

1921-70-6 structure

1921-70-6
Literature: Journal of the Chemical Society, , p. 5706 - 5713
HS Code 2901100000
Summary 2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

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