(1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮
![(1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮结构式](https://image.chemsrc.com/caspic/022/130931-83-8.png)
(1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮结构式
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常用名 | (1S)-(+)-2-氮杂双环[2.2.1]庚-5-烯-3-酮 | 英文名 | (1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one |
|---|---|---|---|---|
| CAS号 | 130931-83-8 | 分子量 | 109.126 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 319.3±0.0 °C at 760 mmHg | |
| 分子式 | C6H7NO | 熔点 | 92-100ºC | |
| MSDS | 中文版 美版 | 闪点 | 167.1±9.8 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
J. Med. Chem. 33 , 17, (1990) (+-)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2- cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6-dichloropyrimidine and cis-4-(hydroxymethyl)cyclopentenylamine (2a) by subsequent preparation of the 5-[(4-chlorophenyl)azo] derivative of the... |
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Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.
Biochem. Biophys. Res. Commun. 161 , 393, (1989) Carbocylic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which may be useful in the treatment of AIDS. We have synthesized the 5'-triphosphate of Carbovir and examined its ability to inhibit human immunodeficiency vi... |
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