(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one Structure
(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one structure
Common Name (1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-one
CAS Number 130931-83-8 Molecular Weight 109.126
Density 1.2±0.1 g/cm3 Boiling Point 319.3±0.0 °C at 760 mmHg
Molecular Formula C6H7NO Melting Point 92-100ºC
MSDS Chinese USA Flash Point 167.1±9.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.

J. Med. Chem. 33 , 17, (1990)

(+-)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2- cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6-dichloropyrimidine and cis-4-(hydroxymethyl)cyclopentenylamine (2a) by subsequent preparation of the 5-[(4-chlorophenyl)azo] derivative of the...

Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases.

Biochem. Biophys. Res. Commun. 161 , 393, (1989)

Carbocylic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which may be useful in the treatment of AIDS. We have synthesized the 5'-triphosphate of Carbovir and examined its ability to inhibit human immunodeficiency vi...

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