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2,4,6-三甲基吡啶

2,4,6-三甲基吡啶结构式
2,4,6-三甲基吡啶结构式
品牌特惠专场
常用名 2,4,6-三甲基吡啶 英文名 2,4,6-Trimethylpyridine
CAS号 108-75-8 分子量 121.180
密度 0.9±0.1 g/cm3 沸点 171.0±9.0 °C at 760 mmHg
分子式 C8H11N 熔点 −43 °C(lit.)
MSDS 中文版 美版 闪点 57.2±0.0 °C
符号 GHS02 GHS06
GHS02, GHS06
信号词 Danger

Ambient preparation and reactions of gas phase silver cluster cations and anions.

Phys. Chem. Chem. Phys. 17 , 18364-73, (2015)

Electrospray ionization of metal salt solutions followed by ambient heating transforms the resulting salt clusters into new species, primarily naked ionic metal clusters. The experiment is done by passing the clusters through a heated coiled loop outside the ...

An easy-to-use excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine, for use in the highly sensitive and selective liquid chromatography analysis of histamine in Japanese soy sauces.

Anal. Chim. Acta 880 , 145-51, (2015)

In this study, a novel pre-column excimer fluorescence derivatization reagent, 2-chloro-4-methoxy-6-(4-(pyren-4-yl)butoxy)-1,3,5-triazine (CMPT), was developed for polyamines, specifically histamine. By CMPT derivatization, the polyamines, histamine and tyram...

Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions.

Sci. Rep. 5 , 12157, (2015)

ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great promise in cellular experiments and animal models of ischemic stroke and pain. Here, we investigate the proposed mechanism of action o...

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Nat. Commun. 5 , 4763, (2014)

Deubiquitylases (DUBs) are key regulators of the ubiquitin system which cleave ubiquitin moieties from proteins and polyubiquitin chains. Several DUBs have been implicated in various diseases and are attractive drug targets. We have developed a sensitive and ...

Studies examining the relationship between the chemical structure of protoxin II and its activity on voltage gated sodium channels.

J. Med. Chem. 57(15) , 6623-31, (2014)

The aqueous solution structure of protoxin II (ProTx II) indicated that the toxin comprises a well-defined inhibitor cystine knot (ICK) backbone region and a flexible C-terminal tail region, similar to previously described NaSpTx III tarantula toxins. In the ...

3-D-QSAR and docking studies on the neuronal choline transporter.

Bioorg. Med. Chem. Lett. 20 , 4870-7, (2010)

The high affinity neuronal choline transporter (CHT1) is responsible for the uptake of choline into the pre-synaptic terminal of cholinergic neurons. Considering our past experience with modeling the blood-brain barrier choline transporter (BBBCHT) as drug de...

White adipose tissue resilience to insulin deprivation and replacement.

PLoS ONE 9(8) , e106214, (2014)

Adipocyte size and body fat distribution are strongly linked to the metabolic complications of obesity. The aim of the present study was to test the plasticity of white adipose tissue in response to insulin deprivation and replacement. We have characterized t...

Structural correlations for (1)H, (13)C and (15)N NMR coordination shifts in Au(III), Pd(II) and Pt(II) chloride complexes with lutidines and collidine.

Magn. Reson. Chem. 48(6) , 417-26, (2010)

(1)H, (13)C and (15)N NMR studies of gold(III), palladium(II) and platinum(II) chloride complexes with dimethylpyridines (lutidines: 2,3-lutidine, 2,3lut; 2,4-lutidine, 2,4lut; 3,5-lutidine, 3,5lut; 2,6-lutidine, 2,6lut) and 2,4,6-trimethylpyridine (2,4,6-col...

Ab initio study of hydrogen bonding and proton transfer in 3:1 FH:NH3 and FH:collidine complexes: structures and one- and two-bond coupling constants across hydrogen bonds.

J. Phys. Chem. A 110(3) , 1128-33, (2006)

Ab initio EOM-CCSD calculations have been performed on 3:1 FH:NH3 complexes at their own optimized MP2/6-31+G(d,p) geometries and at the optimized geometries in the hydrogen-bonding regions of corresponding 3:1 FH:collidine complexes. The isolated gas-phase e...

Absorption spectrometric study of molecular complex formation between [60]fullerene and a series of methylated pyridines.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 58(12) , 2563-9, (2002)

[60]fullerene has been shown to form 1:1 molecular complexes with pyridine and some methylated pyridines such as 2-picoline, 3-picoline, 4-picoline, 2,6-lutidine and 2,4,6-collidine in CCl4 medium by absorption spectrometric method. Well defined charge transf...