2,4,6-Trimethylpyridine

Modify Date: 2025-08-21 08:08:46

2,4,6-Trimethylpyridine Structure
2,4,6-Trimethylpyridine structure
 Common Name 2,4,6-Trimethylpyridine
CAS Number 108-75-8 Molecular Weight 121.180
Density 0.9±0.1 g/cm3 Boiling Point 171.0±9.0 °C at 760 mmHg
Molecular Formula C8H11N Melting Point −43 °C(lit.)
MSDS Chinese USA Flash Point 57.2±0.0 °C
Symbol GHS02 GHS06
GHS02, GHS06		 Signal Word Danger

 Names

Name 2,4,6-Collidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 171.0±9.0 °C at 760 mmHg
Melting Point −43 °C(lit.)
Molecular Formula C8H11N
Molecular Weight 121.180
Flash Point 57.2±0.0 °C
Exact Mass 121.089149
PSA 12.89000
LogP 2.11
Vapour Pressure 1.9±0.3 mmHg at 25°C
Index of Refraction 1.502
Storage condition 2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility 35 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU0970000
CHEMICAL NAME :
Pyridine, 2,4,6-trimethyl-
CAS REGISTRY NUMBER :
108-75-8
BEILSTEIN REFERENCE NO. :
0107283
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H11-N

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 ppm/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,847,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1347 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 712 (estimated) No. of Female Employees: 593 (estimated)

 Safety Information

Symbol GHS02 GHS06
GHS02, GHS06
Signal Word Danger
Hazard Statements H226-H302 + H332-H311-H315-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P312
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R10;R20/21/22;R36/37/38
Safety Phrases S26-S36/37
RIDADR UN 1992 3/PG 3
WGK Germany 3
RTECS UU0970000
Packaging Group III
Hazard Class 3
HS Code 2933399010

 Synthetic Route

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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 Synonyms

Collidine
EINECS 203-613-3
Pyridine, 2,4,6-trimethyl-
γ-collidine
MFCD00006338
2,4,6-trimethylpyridine
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