盐酸甲氧氯普胺
盐酸甲氧氯普胺结构式
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常用名 | 盐酸甲氧氯普胺 | 英文名 | metoclopramide hydrochloride |
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| CAS号 | 54143-57-6 | 分子量 | 354.27 | |
| 密度 | N/A | 沸点 | 418.7ºC at 760mmHg | |
| 分子式 | C14H25Cl2N3O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 207ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates.
Drug Metab. Pharmacokinet. 29(5) , 419-26, (2014) In central nervous system drug discovery, cerebrospinal fluid (CSF) drug concentration (C(CSF)) has been widely used as a surrogate for unbound brain concentrations (C(u,brain)). However, previous rodent studies demonstrated that when drugs undergo active eff... |
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Clinical challenge. Esophageal hiatal hernia.
J. Zoo Wildl. Med. 45(4) , 999-1001, (2014)
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The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis.
Am. J. Gastroenterol. 108(9) , 1382-91, (2013) The relationship between symptom improvement (SI) and acceleration of gastric emptying (GE) for different drugs used in the treatment of idiopathic and diabetic gastroparesis is uncertain. In this paper we examined the study-specific correlations between SI a... |
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Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.
Fundam. Clin. Pharmacol. 29(1) , 86-94, (2015) Several methods are used to evaluate gastric emptying (GE) in rats, which is an important endpoint in preclinical drug development. Although phenol red model or monitoring of plasma acetaminophen levels are well-established procedures for GE assessment, their... |
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Development and Evaluation of Melt-in-Mouth Tablets of Metoclopramide Hydrochloride Using Novel Co-processed Superdisintegrants.
Indian J. Pharm. Sci. 76(5) , 423-9, (2014) In the present investigation, a novel multifunctional co-processed superdisintegrants consisting of crospovidone and Kyron T-314 were fabricated by solvent evaporation method to develop melt-in-mouth tablets of metoclopramide hydrochloride with a view to enha... |
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Acute migraine treatment in emergency settings.
Am. Fam. Physician 89(9) , 742-4, (2014)
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The effects of dexamethasone and metoclopramide on early and late postoperative nausea and vomiting in women undergoing myomectomy under spinal anaesthesia.
Niger. J. Clin. Pract. 17(4) , 449-55, (2014) Post-operative nausea and vomiting (PONV); early or late, has detrimental effects on surgical patients such as surgical wound disruption, esophageal tear and delayed discharge from the post anesthetic care unit. This study evaluated the effects of dexamethaso... |
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Green urine in the intensive care unit: is this clinically relevant?
Am. Surg. 81(1) , E32-3, (2015)
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[Clinical toxicology of mushroom poisoning. Clitocybe clavipes, Coprinopsis atramentarius].
Chudoku. Kenkyu. 26(3) , 223-5, (2013)
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Ondansetrone or metoclopromide? Which is more effective in severe nausea and vomiting of pregnancy? A randomized trial double-blind study.
Clin. Exp. Obstet. Gynecol. 40(1) , 127-30, (2013) Nausea and vomiting of pregnancy (NVP) are seen in 50-80% of pregnancies. However, in severe NVP, called hypermesis gravidarum (HG), medical therapy to reduce nausea and vomiting is inevitable and ondansetron (OND) as an effective drug has recently been propo... |