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| 中文名 | 盐酸胃复安 |
|---|---|
| 英文名 | metoclopramide hydrochloride |
| 中文别名 |
甲氧氯普胺盐酸盐
盐酸甲氧氯普胺 盐酸甲氧氯普胺 N-[(2-二乙氨基)乙基]-4-氨基-2-甲氧基-5-氯-苯甲酰胺盐酸盐 |
| 英文别名 |
Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride (9CI)
Annavar 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide monohydrochloride 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1) 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride (1:1) Metoclopramide hydrochloride [USAN:JAN] 4-Amino-5-chlor-N-[2-(diethylamino)ethyl]-2-methoxybenzolcarboxamidhydrochlorid o-Anisamide, 4-amino-5-chloro-N-[2- (diethylamino)ethyl]-, monohydrochloride GastreseL.A 4-amino-5-chloro-N-[2-(diéthylamino)éthyl]-2-méthoxybenzamide chlorhydrate Benzamide, 4-amino-5-chloro-N-[2- (diethylamino)ethyl]-2-methoxy-, monohydrochloride Metoclopramide Hydrochloride (500 mg) 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-o-anisamide hydrochloride MFCD00150634 benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochloride METOCLOPRAMIDEHYDROCHLORIDE,MONOHYDRATE,USP MetoclopraMide HCI Gastromax 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide hydrochloride metoclopramide monohydrochloride Gastrobidcontinus EINECS 230-634-5 MetoclopraMide Hydrochloride,USP Metoclopramide hydrochloride 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride Metoclopramide (hydrochloride hydrate) |
| 描述 | Metoclopramide盐酸水合物是多巴胺受体D2拮抗剂。 |
|---|---|
| 相关类别 |
| 沸点 | 418.7ºC at 760mmHg |
|---|---|
| 分子式 | C14H25Cl2N3O3 |
| 分子量 | 354.27 |
| 闪点 | 207ºC |
| PSA | 67.59000 |
| LogP | 3.77650 |
| 储存条件 | 室温，干燥 |
|
Section 1. Chemical Product and Company Identification Metoclopramide HClCatalog ME176 Common Name/ Number(s). Trade Name CAS#54143-57-6
Manufacturer RTECSBZ3325000 SPECTRUM CHEMICAL MFG. CORP. TSCATSCA 8(b) inventory: No products were found. Commercial Name(s)Not available. CI# Not available. Synonym4-Amino-5-chloro-N-[(2-diethylamino)ethyl]-2-methoxybenzamide IN CASE OF EMERGENCY hydrochloride Chemical NameNot available. Not available.CALL (310) 516-8000 Chemical Family Chemical FormulaC14H22ClN3O2.HCl.H2O SPECTRUM CHEMICAL MFG. CORP. Section 2.Composition and Information on Ingredients Exposure Limits TWA (mg/m3)STEL (mg/m3) CEIL (mg/m3) NameCAS #% by Weight 1) Metoclopramide HCl54143-57-6100 Toxicological DataMetoclopramide HCl on IngredientsLD50: Not available. LC50: Not available. Section 3. Hazards Identification Potential Acute Health Effects Very hazardous in case of skin contact (irritant), of ingestion, of inhalation. Hazardous in case of eye contact (irritant). Potential Chronic HealthVery hazardous in case of skin contact (irritant), of ingestion, of inhalation. EffectsHazardous in case of eye contact (irritant). CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to the nervous system. Repeated or prolonged exposure to the substance can produce target organs damage. Metoclopramide HCl Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention. Skin ContactAfter contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Serious Skin ContactWash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. InhalationAllow the victim to rest in a well ventilated area. Seek immediate medical attention. Serious InhalationNot available. IngestionDo not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Flash PointsNot available. Flammable LimitsNot available. These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds. Products of Combustion Fire Hazards in Presence of Not available. Various Substances Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available. of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available. Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks onNot available. Fire Hazards Special Remarks on Explosion Not available. Hazards Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large Spill Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Metoclopramide HCl Section 7. Handling and Storage PrecautionsKeep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek medical attention and show the label when possible. Avoid contact with skin and eyes Keep away from incompatibles such as oxidizing agents. StorageKeep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Crystalline solid.)OdorOdorless. TasteNot available. 354.28 g/mole Molecular Weight ColorWhite to yellowish. (Light.) pH (1% soln/water)Not available. Decomposes. Boiling Point Melting Point183°C (361.4°F) Not available. Critical Temperature Specific GravityNot available. Vapor PressureNot applicable. Vapor DensityNot available. VolatilityNot available. Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Not available. Ionicity (in Water) Dispersion PropertiesSee solubility in water, methanol. SolubilityPartially soluble in cold water, hot water, methanol. Metoclopramide HCl Section 10. Stability and Reactivity Data The product is stable. Stability Instability TemperatureNot available. Not available. Conditions of Instability Reactive with oxidizing agents. Incompatibility with various substances CorrosivityNot available. Special Remarks onNot available. Reactivity Special Remarks onNot available. Corrosivity PolymerizationNo. Section 11. Toxicological Information Routes of EntryEye contact. Inhalation. Ingestion. Toxicity to AnimalsLD50: Not available. LC50: Not available. Chronic Effects on Humans The substance is toxic to the nervous system. Other Toxic Effects onVery hazardous in case of skin contact (irritant), of ingestion, of inhalation. Humans Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherNot available. Toxic Effects on Humans Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are more toxic. Toxicity of the Products of Biodegradation Special Remarks on theNot available. Products of Biodegradation Metoclopramide HCl Section 13. Disposal Considerations Waste Disposal Section 14. Transport Information DOT ClassificationNot a DOT controlled material (United States). Not applicable. Identification Not applicable. Special Provisions for Transport DOT (Pictograms) Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations California Proposition 65 Warnings Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC). Other Classifications DSCL (EEC)R36/38- Irritating to eyes and skin. Health Hazard HMIS (U.S.A.)2 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 2 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) Metoclopramide HCl ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. SECTION 16 - ADDITIONAL INFORMATION N/A |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H302-H315-H319-H335 |
| 警示性声明 | P301 + P312 + P330-P305 + P351 + P338 |
| 危险品运输编码 | NONH for all modes of transport |