N-羟甲基氯乙酰胺
N-羟甲基氯乙酰胺结构式
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常用名 | N-羟甲基氯乙酰胺 | 英文名 | N-Methylolchloroacetamide |
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| CAS号 | 2832-19-1 | 分子量 | 123.538 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 374.0±27.0 °C at 760 mmHg | |
| 分子式 | C3H6ClNO2 | 熔点 | 100-105 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 180.0±23.7 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
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Formaldehyde-releasers: relationship to formaldehyde contact allergy. Part 2: Metalworking fluids and remainder.
Contact Dermatitis 63(3) , 129-39, (2010) We have reviewed formaldehyde-releasers used in metalworking fluids (MWFs) in this and a previous part of a two-part article. These biocides do not appear to be frequent or important sensitizers. Even in highly selected patient groups of metalworkers, mean pr... |
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Formaldehyde-releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde-releasers.
Contact Dermatitis 61(2) , 63-85, (2009) This is one of series of review articles on formaldehyde and formaldehyde-releasers (others: formaldehyde in cosmetics, in clothes and in metalworking fluids and miscellaneous). Thirty-five chemicals were identified as being formaldehyde-releasers. Although a... |
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Effect of Prolonged Repeated Exposure to Formaldehyde Donors with Doses Below the EC3 Value on Draining Lymph Node Responses.
J. Immunotoxicol. 4(3) , 239-46, (2007) In the Local Lymph Node Assay (LLNA), a stimulation index of 3 (SI = 3) is established as a threshold value for hazard identification of sensitization. The corresponding EC3 value, the effective concentration inducing a threefold increase compared to controls... |
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Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design.
J. Med. Chem. 44(13) , 2080-93, (2001) In our continuation of the structure-based design of anti-trypanosomatid drugs, parasite-selective adenosine analogues were identified as low micromolar inhibitors of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Crystal structures of Trypanosoma brucei, ... |
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Occupational contact dermatitis to N-methylol-chloracetamide.
Contact Dermatitis 17(3) , 182-4, (1987)
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Allergic contact dermatitis from the preservative N-methylol-chloracetamide.
Contact Dermatitis 6(4) , 302-3, (1980)
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Chloracetamide-N-metholol: an example of an in vitro and in vivo clastogen which is non-mutagenic to Salmonella.
Mutat. Res. 156(1-2) , 19-32, (1985) The industrial biocide chloracetamide-N-metholol (CAM) has been shown to be non-mutagenic to 6 strains of Salmonella using both the plate-incorporation and a pre-incubation test protocol. Its biocidal activity is unlikely to have influenced these results sinc... |
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The amidomethylation of some N, N-dialkylanilines (Tscherniac-Einhorn reaction). Gale DJ and Wilshire JFK.
Aust. J. Chem. 28(11) , 2447-2458, (1975)
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