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IMD-0354

IMD-0354结构式
IMD-0354结构式
品牌特惠专场
常用名 IMD-0354 英文名 IMD 0354
CAS号 978-62-1 分子量 383.67300
密度 1.561g/cm3 沸点 323.1ºC at 760 mmHg
分子式 C15H8ClF6NO2 熔点 N/A
MSDS 中文版 美版 闪点 149.2ºC
符号 GHS07
GHS07
信号词 Warning

Interleukin 34: a new modulator of human and experimental inflammatory bowel disease.

Clin. Sci. (Lond.) 129 , 281-90, (2015)

IBD (inflammatory bowel disease), where CD (Crohn's disease) and UC (ulcerative colitis) represent the two main forms, are chronic inflammatory conditions of the intestine. Macrophages play a central role in IBD pathogenesis and are regulated by major differe...

TGF-β1 activates the canonical NF-κB signaling to promote cell survival and proliferation in dystrophic muscle fibroblasts in vitro.

Biochem. Biophys. Res. Commun. 471 , 576-81, (2016)

Activated fibroblasts continue to proliferate at injury sites, leading to progressive muscular fibrosis in Duchenne muscular dystrophy (DMD). TGF-β1 is a dominant profibrotic mediator thought to play a critical role in muscle fibrosis; however, the implicated...