N-Arachidonyl maleimide
N-Arachidonyl maleimide结构式
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常用名 | N-Arachidonyl maleimide | 英文名 | N-Arachidonyl maleimide |
|---|---|---|---|---|
| CAS号 | 876305-42-9 | 分子量 | 369.540 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 492.9±34.0 °C at 760 mmHg | |
| 分子式 | C24H35NO2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 185.2±18.0 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling.
ChemBioChem. 11 , 218-27, (2010) 2-Arachidonoylglycerol plays a major role in endocannabinoid signaling, and is tightly regulated by the monoacylglycerol lipase (MAGL). Here we report the crystal structure of human MAGL. The protein crystallizes as a dimer, and despite structural homologies ... |
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Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes.
Chem. Biol. 12 , 649-56, (2005) We have previously reported that the endocannabinoid, 2-arachidonoyl-glycerol (2-AG), is hydrolyzed in rat cerebellar membranes by monoglyceride lipase (MGL)-like enzymatic activity. The present study shows that, like MGL, 2-AG-degrading enzymatic activity is... |
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