半胱胺S-磷酸盐 钠盐
半胱胺S-磷酸盐 钠盐结构式
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常用名 | 半胱胺S-磷酸盐 钠盐 | 英文名 | Ethanethiol, 2-amino-,1-(dihydrogen phosphate), sodium salt (1:1) |
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| CAS号 | 3724-89-8 | 分子量 | 179.11000 | |
| 密度 | 1.597g/cm3 | 沸点 | 384.2ºC at 760mmHg | |
| 分子式 | C2H7NNaO3PS | 熔点 | 220ºC (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 186.2ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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A comparison of the effectiveness of cysteamine and phosphocysteamine in elevating plasma cysteamine concentration and decreasing leukocyte free cystine in nephropathic cystinosis.
Pediatr. Res. 23(6) , 616-20, (1988) Cysteamine (beta-mercaptoethylamine, MEA) is currently used to treat children with nephropathic cystinosis. In this study MEA was compared to phosphocysteamine (MEAP), a phosphorothioester that tastes and smells better than MEA, with respect to its ability to... |
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The treatment of cystinosis with cysteamine and phosphocysteamine in the United Kingdom and Eire.
Pediatr. Nephrol. 9(6) , 685-9, (1995) Fifty-nine patients with cystinosis were treated with cysteamine or phosphocysteamine in the United Kingdom up to May 1990. Treatment was started at a median age of 3.2 years (range 0.6-24.8 years) and continued for a median duration of 3.0 years (range 0.01-... |
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Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis.
J. Inherit. Metab. Dis. 35(5) , 847-57, (2012) Infantile neuronal ceroid lipofuscinosis (INCL) is a profoundly neurodegenerative disease of children caused by a deficiency in the lysosomal enzyme palmitoyl protein thioesterase-1 (PPT1). There is currently no effective therapy for this invariably fatal dis... |
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Effects of oral phosphocysteamine and rectal cysteamine in cystinosis.
Arch. Dis. Child. 66(12) , 1434-7, (1991) Diurnal variation in leucocyte cystine and the effects of equimolar single doses of oral phosphocysteamine and rectal cysteamine were studied in eight patients with cystinosis, aged 1.8-16.5 years. No significant diurnal variation in leucocyte cystine was fou... |
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[The effect of phenol derivatives on the antimutagenic activity of dextran].
Izv. Akad. Nauk Ser. Biol. (4) , 613-7, (1993) The effects of dextran + hydrazine or amino derivative of dibunol and of dextran + cystafos derivatives with different degree of modification of their molecules on the mutagenic activity of gamma irradiation were studied using the micronucleus test in polychr... |
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[Ways of reducing the toxicity of chemotherapy of cancer of the ovaries].
Sov. Med. (5) , 24-8, (1986)
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[The antimutagenic activity of compounds of modified polyglucin].
Izv. Akad. Nauk SSSR Biol. (4) , 625-8, (1990) The effect of modified polygluquin compounds on gamma-irradiated nuclei of V-79 Chinese hamster cells has been studied. Antimutagenic properties of the compounds are determined by aldehyde groups and oxidized chains. |
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Influence of a radioprotector WR-638 on the lymphoid compartment of the irradiated rat thymus: a flow cytometric analysis.
Int. J. Radiat. Biol. 66(2) , 143-50, (1994) The T cell composition of the thymus of X-ray irradiated (3.5 Gy) Wistar rat protected with WR-638 was analyzed by flow cytometry using monoclonal antibodies directed to the Thy 1.1, CD43, CD2, CD5, CD4, CD8 and class I and II MHC antigens. It was shown that ... |
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Effects of pre- and postnatal cysteamine exposure on renal function in the rat.
Pediatr. Nephrol. 13(9) , 812-5, (1999) The safety of cysteamine after renal transplantation and during pregnancy is an important issue, since girls with cystinosis are in better health on cysteamine therapy and thus more likely to become pregnant. In the first study, cysteamine was given to pregna... |
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Renal stones in nephropathic cystinosis treated with phosphocysteamine.
Pediatr. Nephrol. 11(6) , 787-8, (1997)
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