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4-溴-2-氯-1-氟苯

一般危化品
4-溴-2-氯-1-氟苯结构式
4-溴-2-氯-1-氟苯结构式
常用名 4-溴-2-氯-1-氟苯 英文名 4-Bromo-2-chloro-1-fluorobenzene
CAS号 60811-21-4 分子量 209.443
密度 1.7±0.1 g/cm3 沸点 196.4±20.0 °C at 760 mmHg
分子式 C6H3BrClF 熔点 N/A
MSDS 中文版 美版 闪点 72.6±21.8 °C
符号 GHS07 GHS09
GHS07, GHS09
信号词 Warning

Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor.

Chemistry 20(1) , 263-71, (2014)

Conducting low-temperature organometallic reactions under continuous flow conditions offers the potential to more accurately control exotherms and thus provide more reproducible and scalable processes. Herein, progress towards this goal with regards to the li...

Efficient synthesis of a GABA A alpha2,3-selective allosteric modulator via a sequential Pd-catalyzed cross-coupling approach.

J. Org. Chem. 70(15) , 6034-6039, (2005)

A practical synthesis of 2-[3-(4-fluoro-3-pyridin-3-yl-phenyl)-imidazo[1,2-a]pyrimidin-7-yl]-propan-2-ol (1), an oral GABA(A) alpha(2/3)-selective agonist, is described. The five-step process, which afforded 1 in 40% overall yield, included imidazopyrimidine ...