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新戊酰基乙腈

新戊酰基乙腈结构式
新戊酰基乙腈结构式
品牌特惠专场
常用名 新戊酰基乙腈 英文名 Pivaloylacetonitrile
CAS号 59997-51-2 分子量 125.168
密度 0.9±0.1 g/cm3 沸点 236.0±0.0 °C at 760 mmHg
分子式 C7H11NO 熔点 66-69 °C(lit.)
MSDS 中文版 美版 闪点 59.5±19.8 °C
符号 GHS06
GHS06
信号词 Danger

Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.

J. Med. Chem. 45(14) , 2994-3008, (2002)

We report on a series of N-pyrazole, N'-aryl ureas and their mode of binding to p38 mitogen activated protein kinase. Importantly, a key binding domain that is distinct from the adenosine 5'-triphoshate (ATP) binding site is exposed when the conserved activat...

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols.

Org. Biomol. Chem. 4(1) , 116-25, (2006)

Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, n...