Pivaloylacetonitrile
Pivaloylacetonitrile structure
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Common Name | Pivaloylacetonitrile | ||
|---|---|---|---|---|
| CAS Number | 59997-51-2 | Molecular Weight | 125.168 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 236.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C7H11NO | Melting Point | 66-69 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 59.5±19.8 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Pyrazole urea-based inhibitors of p38 MAP kinase: from lead compound to clinical candidate.
J. Med. Chem. 45(14) , 2994-3008, (2002) We report on a series of N-pyrazole, N'-aryl ureas and their mode of binding to p38 mitogen activated protein kinase. Importantly, a key binding domain that is distinct from the adenosine 5'-triphoshate (ATP) binding site is exposed when the conserved activat... |
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Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols.
Org. Biomol. Chem. 4(1) , 116-25, (2006) Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, n... |
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