水杨酰苯胺
水杨酰苯胺结构式
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常用名 | 水杨酰苯胺 | 英文名 | Salicylanilide |
|---|---|---|---|---|
| CAS号 | 87-17-2 | 分子量 | 213.232 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 294.3±23.0 °C at 760 mmHg | |
| 分子式 | C13H11NO2 | 熔点 | 136-138 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 131.8±22.6 °C | |
| 符号 |
GHS07, GHS09 |
信号词 | Warning |
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A closer study of peak distortions in supercritical fluid chromatography as generated by the injection.
J. Chromatogr. A. 1400 , 131-9, (2015) In SFC the sample cannot be dissolved in the mobile phase, so it is often dissolved in pure modifier, or another liquid, sometimes resulting in serious distortions of the eluted peak profiles already at moderately high injection volumes. It is suspected the r... |
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Application of reactive salicylanilide to viscose fabrics as antibacterial and antifungus finishing.
Int. J. Biol. Macromol. 50(1) , 273-6, (2012) In the present study salicylanilide was reacted with 2,4,6-trichloro-1,3,5-triazine producing reactive salicylanilide at a yield of 45% according to reaction conditions set. The reactive salicylanilide was confirmed structurally through FT-IR analysis. Pristi... |
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Harmaline-resistant mutant of Methanothermobacter thermautotrophicus with a lesion in Na(+)/H(+) antiport.
Gen. Physiol. Biophys. 30 Spec No , S54-60, (2011) A spontaneous mutant of Methanothermobacter thermautotrophicus resistant to the Na(+)/H(+) antiporter inhibitor harmaline was isolated. The Na(+)/H(+) exchange activity in the mutant cells was remarkably decreased in comparison with wild-type cells. Na(+)/H(+... |
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Salicylanilide carbamates: antitubercular agents active against multidrug-resistant Mycobacterium tuberculosis strains.
Bioorg. Med. Chem. 18 , 1054-61, (2010) A series of 27 salicylanilide-based carbamates was prepared as a part of our ongoing search for new antituberculosis drugs. These compounds exhibited very good in vitro activity against Mycobacterium tuberculosis, Mycobacterium kansasii and Mycobacterium aviu... |
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Salicylanilide esters of N-protected amino acids as novel antimicrobial agents.
Bioorg. Med. Chem. Lett. 19 , 348-51, (2009) A series of novel, highly antimicrobial salicylanilide esters of N-protected amino acids were synthesized and characterized. Their in vitro antimicrobial activity against eight fungal strains and Mycobacterium tuberculosis was determined. The compounds had th... |
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Salicylanilide acetates: synthesis and antibacterial evaluation.
Molecules 12(1) , 1-12, (2007) A new series of salicylanilide acetates was synthesized and evaluated for their in vitro antifungal and antituberculotic activity. Some of the evaluated compounds possessed comparable or better antifungal activity than a fluconazole standard. All these compou... |
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Role of a small molecular weight phosphoprotein in the mechanism of action of CI-994 (N-acetyldinaline).
Int. J. Cancer 62(5) , 636-42, (1995) The mechanism of action of the novel anti-cancer compound CI-994 was studied in C26 murine colon tumor and HCT-8 human colon adenocarcinoma cells. Treatment of either cell line resulted in the specific loss of a 16-kDa phosphoprotein in a time- and concentrat... |
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In vitro antibacterial and antifungal activity of salicylanilide benzoates.
ScientificWorldJournal 2012 , 290628, (2012) The resistance to antimicrobial agents brings a need of novel antimicrobial agents. We have synthesized and found the in vitro antibacterial activity of salicylanilide esters with benzoic acid (2-(phenylcarbamoyl)phenyl benzoates) in micromolar range. They we... |
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Photosynthesis-Inhibiting efficiency of 4-chloro-2-(chlorophenylcarbamoyl)phenyl alkylcarbamates.
Bioorg. Med. Chem. Lett. 21(15) , 4564-7, (2011) A series of photosynthetic electron transport (PET) inhibitors from the group of salicylanilide alkylcarbamates was investigated. The compounds were analyzed using RP-HPLC to determine lipophilicity, and their PET inhibition was determined in spinach (Spinaci... |
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A comparison of the metabolism and elimination of benzanilide and salicylanilide in the rat.
Xenobiotica 12(2) , 93-9, (1982) 1. The metabolism and elimination of benzanilide and salicylanilide in rats were compared. 2. For both compounds, greater than 70% dose was excreted in urine with 20% in faeces, in 3 days. 3. With [14C]benzanilide and [14C]salicylanilide, 40% and 35% respecti... |