2-氟-3,3-二甲基-2,3-二氢-1,2-苯并异噻唑 1,1-二氧化物
2-氟-3,3-二甲基-2,3-二氢-1,2-苯并异噻唑 1,1-二氧化物结构式
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常用名 | 2-氟-3,3-二甲基-2,3-二氢-1,2-苯并异噻唑 1,1-二氧化物 | 英文名 | 2,3-DIHYDRO-3,3-DIMETHYL-2-FLUORO-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE |
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| CAS号 | 124170-23-6 | 分子量 | 215.24500 | |
| 密度 | 1.41g/cm3 | 沸点 | 307.6ºC at 760 mmHg | |
| 分子式 | C9H10FNO2S | 熔点 | 115-117ºC | |
| MSDS | 中文版 美版 | 闪点 | 139.9ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.
J. Med. Chem. 54(1) , 78-94, (2011) A novel series of AMPAR positive modulators is described that were identified by high throughput screening. The molecules of the series have been optimized from a high quality starting point hit to afford excellent developability, tolerability, and efficacy p... |
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E. Differding et al.
Tetrahedron Lett. 32 , 1779, (1991)
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E. Differding, M. Wehrli
Tetrahedron Lett. 32 , 3819, (1991)
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