2,3-DIHYDRO-3,3-DIMETHYL-2-FLUORO-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE
2,3-DIHYDRO-3,3-DIMETHYL-2-FLUORO-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE structure
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Common Name | 2,3-DIHYDRO-3,3-DIMETHYL-2-FLUORO-1,2-BENZISOTHIAZOLE 1,1-DIOXIDE | ||
|---|---|---|---|---|
| CAS Number | 124170-23-6 | Molecular Weight | 215.24500 | |
| Density | 1.41g/cm3 | Boiling Point | 307.6ºC at 760 mmHg | |
| Molecular Formula | C9H10FNO2S | Melting Point | 115-117ºC | |
| MSDS | Chinese USA | Flash Point | 139.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.
J. Med. Chem. 54(1) , 78-94, (2011) A novel series of AMPAR positive modulators is described that were identified by high throughput screening. The molecules of the series have been optimized from a high quality starting point hit to afford excellent developability, tolerability, and efficacy p... |
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E. Differding et al.
Tetrahedron Lett. 32 , 1779, (1991)
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E. Differding, M. Wehrli
Tetrahedron Lett. 32 , 3819, (1991)
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