4-(1H-咪唑基-4-甲基)哌啶二氢溴酸盐
4-(1H-咪唑基-4-甲基)哌啶二氢溴酸盐结构式
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常用名 | 4-(1H-咪唑基-4-甲基)哌啶二氢溴酸盐 | 英文名 | Immepip, Dihydrobromide |
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| CAS号 | 164391-47-3 | 分子量 | 327.05900 | |
| 密度 | N/A | 沸点 | 430.2ºC at 760mmHg | |
| 分子式 | C9H17Br2N3 | 熔点 | 234-235 °C | |
| MSDS | 中文版 美版 | 闪点 | 214ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction.
Microcirculation 22 , 237-48, (2015) The mechanisms by which histamine increases microvascular permeability remain poorly understood. We tested the hypothesis that H1 receptor activation disrupts the endothelial barrier and investigated potential downstream signals.We used confluent EC monolayer... |
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Histamine H3 receptor activation counteracts adenosine A2A receptor-mediated enhancement of depolarization-evoked [3H]-GABA release from rat globus pallidus synaptosomes.
ACS Chem. Neurosci. 5(8) , 637-45, (2014) High levels of histamine H3 receptors (H3Rs) are found in the globus pallidus (GP), a neuronal nucleus in the basal ganglia involved in the control of motor behavior. By using rat GP isolated nerve terminals (synaptosomes), we studied whether H3R activation m... |
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Development of time-resolved fluorescent based [EU]-GTP binding assay for selection of human Histamine 3 receptor antagonists/inverse agonist: a potential target for Alzheimer's treatment.
Ann Neurosci 19 , 71-5, (2014) The histamine H3 receptor is an attractive G protein-coupled receptor drug target that regulates neurotransmission in the central nervous system and plays a crucial role in cognitive and homeostatic functions. This receptor exhibits molecular, pharmacological... |