Immepip, Dihydrobromide
Modify Date: 2024-01-02 17:45:16
Immepip, Dihydrobromide structure
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Common Name | Immepip, Dihydrobromide | ||
|---|---|---|---|---|
| CAS Number | 164391-47-3 | Molecular Weight | 327.05900 | |
| Density | N/A | Boiling Point | 430.2ºC at 760mmHg | |
| Molecular Formula | C9H17Br2N3 | Melting Point | 234-235 °C | |
| MSDS | Chinese USA | Flash Point | 214ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Immepip, DihydrobromideImmepip dihydrobromide is a H3 agonist. Immepip dihydrobromide can reduce cortical histamine release. Immepip dihydrobromide can be used for the research of neurological diseases[1]. |
| Name | Immepip, Dihydrobromide |
|---|---|
| Synonym | More Synonyms |
| Description | Immepip dihydrobromide is a H3 agonist. Immepip dihydrobromide can reduce cortical histamine release. Immepip dihydrobromide can be used for the research of neurological diseases[1]. |
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| Related Catalog | |
| In Vivo | Immepip dihydrobromide (腹腔注射；5 mg/kg，10 mg/kg) 显著减少皮质组胺释放，且微弱地促进大鼠睡眠[1]。 |
| Boiling Point | 430.2ºC at 760mmHg |
|---|---|
| Melting Point | 234-235 °C |
| Molecular Formula | C9H17Br2N3 |
| Molecular Weight | 327.05900 |
| Flash Point | 214ºC |
| Exact Mass | 324.97900 |
| PSA | 40.71000 |
| LogP | 3.19680 |
| Vapour Pressure | 6.32E-08mmHg at 25°C |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction.
Microcirculation 22 , 237-48, (2015) The mechanisms by which histamine increases microvascular permeability remain poorly understood. We tested the hypothesis that H1 receptor activation disrupts the endothelial barrier and investigated ... |
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Histamine H3 receptor activation counteracts adenosine A2A receptor-mediated enhancement of depolarization-evoked [3H]-GABA release from rat globus pallidus synaptosomes.
ACS Chem. Neurosci. 5(8) , 637-45, (2014) High levels of histamine H3 receptors (H3Rs) are found in the globus pallidus (GP), a neuronal nucleus in the basal ganglia involved in the control of motor behavior. By using rat GP isolated nerve te... |
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Development of time-resolved fluorescent based [EU]-GTP binding assay for selection of human Histamine 3 receptor antagonists/inverse agonist: a potential target for Alzheimer's treatment.
Ann Neurosci 19 , 71-5, (2014) The histamine H3 receptor is an attractive G protein-coupled receptor drug target that regulates neurotransmission in the central nervous system and plays a crucial role in cognitive and homeostatic f... |
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