VUF8430 dihydrobromide

Modify Date: 2024-01-01 20:11:06

VUF8430 dihydrobromide structure	Common Name	VUF8430 dihydrobromide
	CAS Number	100130-32-3	Molecular Weight	323.05300
	Density	N/A	Boiling Point	348.8ºC at 760 mmHg
	Molecular Formula	C₄H₁₃Br₂N₅S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	164.8ºC
	Symbol	GHS07	Signal Word	Warning

Use of VUF8430 dihydrobromide

VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].

Name	2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester S-(2-guanidylethyl)-isothiourea
Synonym	More Synonyms

Description	VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
References	[1]. Lim HD, et al. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49(23):6650-1.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,22,1957

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
RIDADR	NONH for all modes of transport
RTECS	UM6960000

2-Carbamimidamidoethyl carbamimidothioate dihydrobromide

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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