4-乙氧基亚甲基-2-苯基恶唑啉-5-酮
4-乙氧基亚甲基-2-苯基恶唑啉-5-酮结构式
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常用名 | 4-乙氧基亚甲基-2-苯基恶唑啉-5-酮 | 英文名 | 4-ethoxymethylene-2-phenyl-2-oxazolin-5-one |
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| CAS号 | 15646-46-5 | 分子量 | 217.22 | |
| 密度 | 1.18 g/cm3 | 沸点 | 308.8ºC at 760 mmHg | |
| 分子式 | C12H11NO3 | 熔点 | 94-96 °C (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 136.8ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
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Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-α.
Immunology 144(1) , 139-48, (2015) Upon antigen/allergen recognition, epidermal Langerhans' cells (LC) are mobilized and migrate to the local lymph node where they play a major role in initiating or regulating immune responses. It had been proposed that all chemical allergens induce LC migrati... |
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Paradoxical benefits of psychological stress in inflammatory dermatoses models are glucocorticoid mediated.
J. Invest. Dermatol. 134(12) , 2890-7, (2014) Acute psychological stress (PS) mobilizes metabolic responses that are of immediate benefit to the host, but the current medical paradigm holds that PS exacerbates systemic and cutaneous inflammatory disorders. Although the adverse consequences of PS are usua... |
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UVA irradiation of the eye modulates the contact hypersensitivity of the skin and intestines by affecting mast cells in mice.
Photodermatol. Photoimmunol. Photomed. 31(3) , 129-40, (2015) Ultraviolet A (UVA) irradiation before allergic sensitization induces immunosuppression, but the precise mechanism remained unclear. In this study, we examined the influence of UVA irradiation of the eye on contact hypersensitivity (CHS) and the role of mast ... |
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Spectral characteristics of 4-(p-N,N-dimethyl-aminophenylmethylene)-2-phenyl-5-oxazolone (DPO) in different media.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 95 , 679-84, (2012) The absorption and fluorescence characteristics of 4-(p-N,N-dimethyl-aminophenylmethylene)-2-phenyl-5-oxazolone (DPO) have been investigated in different solvents. DPO dye exhibits a large red shift in both absorption and emission spectra as solvent polarity ... |
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CCL25/CCR9 interactions regulate the function of iNKT cells in oxazolone-induced colitis in mice.
PLoS ONE 9(6) , e100167, (2014) Natural killer T (NKT) cells share phenotypic and functional properties with both conventional natural killer cells and T cells. These cells might have an important role in the pathogenesis of ulcerative colitis (UC). The interaction of chemokine ligand 25 (C... |
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John Cornforth (1917-2013).
Nature 506(7486) , 35, (2014)
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Tobacco smoke-induced immunologic changes may contribute to oral carcinogenesis.
J. Investig. Med. 62(2) , 316-23, (2014) The objective of this study was to determine if tobacco smoke (TS), a risk factor for cancers of the aerodigestive tract, may contribute to oral carcinogenesis, in part, by suppressing local immunity.Mice were placed in Plexiglas holders in which they breathe... |
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A quantitative approach to assess the potency of skin sensitizers in the elicitation phase
Toxicology 299(1) , 20-4, (2012) The concept that thresholds exist for the induction of allergic contact dermatitis by chemicals with skin sensitizing properties has been used for a quantitative risk assessment approach. In this approach the potency of skin sensitizers as determined in the L... |
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Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38.
EMBO J. 33(10) , 1117-33, (2014) Macrophages contribute to tissue homeostasis and influence inflammatory responses by modulating their phenotype in response to the local environment. Understanding the molecular mechanisms governing this plasticity would open new avenues for the treatment for... |
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Local and systemic effects of co-stimulatory blockade using cytotoxic T lymphocyte antigen-4-immunoglobulin in dinitrofluorobenzene- and oxazolone-induced contact hypersensitivity in mice.
Clin. Exp. Immunol. 171(2) , 220-30, (2013) Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4)-immunoglobulin (Ig) has immunosuppressive properties both in vivo and in vitro, but much is still unknown about the mechanisms by which CTLA-4-Ig exerts its immunosuppressive activities in vivo. The aim of ... |