4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺
![4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺结构式](https://image.chemsrc.com/caspic/036/16673-34-0.png)
4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺结构式
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常用名 | 4-[2-(5-氯-2-甲氧基苯甲酰氨基)乙基]苯磺酰胺 | 英文名 | NLRP3-IN-2 |
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| CAS号 | 16673-34-0 | 分子量 | 368.835 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C16H17ClN2O4S | 熔点 | 209-214 °C | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.
J. Cardiovasc. Pharmacol. 63(4) , 316-22, (2014) The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hyp... |
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Trendelenburg G.
J. Cereb. Blood Flow Metab. , (2014)
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Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction. Takahashi M.
Int. Heart J. 55(4) , 380, (2014)
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