NLRP3-IN-2
NLRP3-IN-2 structure
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Common Name | NLRP3-IN-2 | ||
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| CAS Number | 16673-34-0 | Molecular Weight | 368.835 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H17ClN2O4S | Melting Point | 209-214 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
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A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse.
J. Cardiovasc. Pharmacol. 63(4) , 316-22, (2014) The formation of the NLRP3 inflammasome in the heart during acute myocardial infarction amplifies the inflammatory response and mediates further damage. Glyburide has NLRP3 inhibitory activity in vitro but requires very high doses in vivo, associated with hyp... |
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Trendelenburg G.
J. Cereb. Blood Flow Metab. , (2014)
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Reply to Letter Regarding Article," NLRP3 Inflammasome as a Therapeutic Target in Myocardial Infarction. Takahashi M.
Int. Heart J. 55(4) , 380, (2014)
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