(S)-1-N-叔丁氧羰基-3-羟基吡咯烷
(S)-1-N-叔丁氧羰基-3-羟基吡咯烷结构式
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常用名 | (S)-1-N-叔丁氧羰基-3-羟基吡咯烷 | 英文名 | (S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate |
|---|---|---|---|---|
| CAS号 | 101469-92-5 | 分子量 | 187.24 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 273.3±33.0 °C at 760 mmHg | |
| 分子式 | C9H17NO3 | 熔点 | 60-64 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 119.1±25.4 °C | |
| 符号 |
GHS05, GHS06 |
信号词 | Danger |
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New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.
J. Med. Chem. 46 , 4543, (2003) Isophthalic acid bis(l-prolyl-pyrrolidine) amide is a very potent prolyl oligopeptidase inhibitor, but it has a log P value of -0.2, which is very low for a compound targeted to the brain. Therefore, these types of compounds were further modified to improve t... |
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