(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate structure
|
Common Name | (S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate | ||
|---|---|---|---|---|
| CAS Number | 101469-92-5 | Molecular Weight | 187.24 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 273.3±33.0 °C at 760 mmHg | |
| Molecular Formula | C9H17NO3 | Melting Point | 60-64 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 119.1±25.4 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
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New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.
J. Med. Chem. 46 , 4543, (2003) Isophthalic acid bis(l-prolyl-pyrrolidine) amide is a very potent prolyl oligopeptidase inhibitor, but it has a log P value of -0.2, which is very low for a compound targeted to the brain. Therefore, these types of compounds were further modified to improve t... |
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