1-金刚烷基溴甲酮
1-金刚烷基溴甲酮结构式
|
常用名 | 1-金刚烷基溴甲酮 | 英文名 | 1-Adamantyl bromomethyl ketone |
|---|---|---|---|---|
| CAS号 | 5122-82-7 | 分子量 | 257.16700 | |
| 密度 | 1.439g/cm3 | 沸点 | 320.3ºC at 760 mmHg | |
| 分子式 | C12H17BrO | 熔点 | 76-79 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 61.1ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
ChemMedChem 6 , 1439-51, (2011) 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a key role in converting intracellular cortisone to physiologically active cortisol, which is implicated in the development of several phenotypes of metabolic syndrome. Inhibition of 11β-HSD1 activity w... |
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