1-Adamantyl bromomethyl ketone
1-Adamantyl bromomethyl ketone structure
|
Common Name | 1-Adamantyl bromomethyl ketone | ||
|---|---|---|---|---|
| CAS Number | 5122-82-7 | Molecular Weight | 257.16700 | |
| Density | 1.439g/cm3 | Boiling Point | 320.3ºC at 760 mmHg | |
| Molecular Formula | C12H17BrO | Melting Point | 76-79 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 61.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.
ChemMedChem 6 , 1439-51, (2011) 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a key role in converting intracellular cortisone to physiologically active cortisol, which is implicated in the development of several phenotypes of metabolic syndrome. Inhibition of 11β-HSD1 activity w... |
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