六氟异丙醇
六氟异丙醇结构式
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常用名 | 六氟异丙醇 | 英文名 | Hexafluoroisopropanol |
|---|---|---|---|---|
| CAS号 | 920-66-1 | 分子量 | 168.038 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 88.9±40.0 °C at 760 mmHg | |
| 分子式 | C3H2F6O | 熔点 | -4ºC | |
| MSDS | 中文版 美版 | 闪点 | 7.6±27.3 °C | |
| 符号 |
GHS05, GHS07, GHS08 |
信号词 | Danger |
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Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.
Int. J. Pharm. 473(1-2) , 334-44, (2014) CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the neuroprotective effect of NGF. CRM197/CL-liposoms were incuba... |
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The effects of organic solvents on the membrane-induced fibrillation of human islet amyloid polypeptide and on the inhibition of the fibrillation.
Biochim. Biophys. Acta 1838(12) , 3162-70, (2014) The organic solvent dimethylsulphoxide (DMSO) and 1,1,1,3,3,3-hexafluoro-2-isopropanol (HFIP) have been widely used as a pre-treating agent of amyloid peptides and as a vehicle for water-insoluble inhibitors. These solvents are left in many cases as a trace q... |
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Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration.
Cells Tissues Organs 200 , 287-99, (2015) Tissue engineering approaches in nerve regeneration search for ways to support gold standard therapy (autologous nerve grafts) and to improve results by bridging nerve defects with different kinds of conduits. In this study, we describe electrospinning of ali... |
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Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus.
Sci. Rep. 5 , 10934, (2015) The acute neurotoxicity of oligomeric forms of amyloid-β 1-42 (Aβ) is implicated in the pathogenesis of Alzheimer's disease (AD). However, how these oligomers might first impair neuronal function at the onset of pathology is poorly understood. Here we have ex... |
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Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.
J. Neuroinflammation 12 , 110, (2015) During inflammation, the kynurenine pathway (KP) metabolises the essential amino acid tryptophan (TRP) potentially contributing to excitotoxicity via the release of quinolinic acid (QUIN) and 3-hydroxykynurenine (3HK). Despite the importance of excitotoxicity... |
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Small expression tags enhance bacterial expression of the first three transmembrane segments of the apelin receptor.
Biochem. Cell Biol. 92(4) , 269-78, (2014) G-protein coupled receptors (GPCRs) are inherently dynamic membrane protein modulators of various important cellular signaling cascades. The apelin receptor (AR or APJ) is a class A GPCR involved in numerous physiological processes, implicated in angiogenesis... |
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Enhancing analysis of cells and proteins by fluorescence imaging on silk-based biomaterials: modulating the autofluorescence of silk.
Tissue Eng. Part C Methods 21(2) , 218-28, (2015) Silk is a versatile and established biomaterial for various tissue engineering purposes. However, it also exhibits strong autofluorescence signals-thereby hindering fluorescence imaging analysis of cells and proteins on silk-derived biomaterials. Sudan Black ... |
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Biocomposite nanofibrous strategies for the controlled release of biomolecules for skin tissue regeneration.
Int. J. Nanomedicine 9 , 4709-22, (2014) Nanotechnology and tissue engineering have enabled engineering of nanostructured strategies to meet the current challenges in skin tissue regeneration. Electrospinning technology creates porous nanofibrous scaffolds to mimic extracellular matrix of the native... |
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Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice.
Neurobiol. Aging 36(1) , 201-10, (2014) Recent evidence supports the amyloid cascade hypothesis that a pathological change of amyloid β (Aβ) in the brain is an initiating event in Alzheimer's disease (AD). Accordingly, modulating the abnormal Aβ aggregation is considered a potential therapeutic tar... |
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Alternative eluent composition for LC-MS analysis of perfluoroalkyl acids in raw fish samples.
J. Agric. Food Chem. 62(23) , 5259-68, (2014) A wide range of anthropogenic pollutants that possess serious environmental and health risks are known. One type of these harmful substances that have become a focus of interest during the past decade are perfluoroalkyl acids (PFAAs), which are extensively us... |