N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍结构式
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常用名 | N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍 | 英文名 | GMX1778 |
|---|---|---|---|---|
| CAS号 | 200484-11-3 | 分子量 | 371.864 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 526.9±58.0 °C at 760 mmHg | |
| 分子式 | C19H22ClN5O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 272.4±32.3 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.
BMC Cancer 15 , 855, (2015) Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in NAD(+) biosynthesis from nicotinamide, is one of the major factors regulating cancer cells metabolism and is considered a promising target for treating cancer. The prototypical NAMPT ... |
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