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N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍

N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍结构式
N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍结构式
品牌特惠专场
常用名 N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍 英文名 GMX1778
CAS号 200484-11-3 分子量 371.864
密度 1.2±0.1 g/cm3 沸点 526.9±58.0 °C at 760 mmHg
分子式 C19H22ClN5O 熔点 N/A
MSDS 中文版 美版 闪点 272.4±32.3 °C
符号 GHS07
GHS07
信号词 Warning

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.

BMC Cancer 15 , 855, (2015)

Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in NAD(+) biosynthesis from nicotinamide, is one of the major factors regulating cancer cells metabolism and is considered a promising target for treating cancer. The prototypical NAMPT ...