GMX1778

GMX1778 Structure
GMX1778 structure
Common Name GMX1778
CAS Number 200484-11-3 Molecular Weight 371.864
Density 1.2±0.1 g/cm3 Boiling Point 526.9±58.0 °C at 760 mmHg
Molecular Formula C19H22ClN5O Melting Point N/A
MSDS Chinese USA Flash Point 272.4±32.3 °C
Symbol GHS07
GHS07
Signal Word Warning

EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.

BMC Cancer 15 , 855, (2015)

Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in NAD(+) biosynthesis from nicotinamide, is one of the major factors regulating cancer cells metabolism and is considered a promising target for treating cancer. The prototypical NAMPT ...