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4-溴苯肼单盐酸盐

4-溴苯肼单盐酸盐结构式
4-溴苯肼单盐酸盐结构式
品牌特惠专场
常用名 4-溴苯肼单盐酸盐 英文名 (4-Bromophenyl)hydrazine hydrochloride
CAS号 622-88-8 分子量 223.498
密度 N/A 沸点 285.6ºC at 760 mmHg
分子式 C6H8BrClN2 熔点 220-230 °C (dec.)(lit.)
MSDS 美版 闪点 126.5ºC
符号 GHS05
GHS05
信号词 Danger

Epoxide-containing side chains enhance antiproliferative activity of paullones.

Eur. J. Med. Chem. 40(7) , 655-61, (2005)

The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for human tumor cell lines. The syntheses were accomplished app...

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.

Bioorg. Med. Chem. Lett. 18(6) , 1926-30, (2008)

A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. One potent orally bioavailable inhibitor had excellent PK p...