(4-Bromophenyl)hydrazine hydrochloride

(4-Bromophenyl)hydrazine hydrochloride Structure
(4-Bromophenyl)hydrazine hydrochloride structure
Common Name (4-Bromophenyl)hydrazine hydrochloride
CAS Number 622-88-8 Molecular Weight 223.498
Density N/A Boiling Point 285.6ºC at 760 mmHg
Molecular Formula C6H8BrClN2 Melting Point 220-230 °C (dec.)(lit.)
MSDS USA Flash Point 126.5ºC
Symbol GHS05
GHS05
Signal Word Danger

Epoxide-containing side chains enhance antiproliferative activity of paullones.

Eur. J. Med. Chem. 40(7) , 655-61, (2005)

The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for human tumor cell lines. The syntheses were accomplished app...

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.

Bioorg. Med. Chem. Lett. 18(6) , 1926-30, (2008)

A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. One potent orally bioavailable inhibitor had excellent PK p...