4-氟-2-三氟甲基苯甲醛
4-氟-2-三氟甲基苯甲醛结构式
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常用名 | 4-氟-2-三氟甲基苯甲醛 | 英文名 | 4-Fluoro-2-(trifluoromethyl)benzaldehyde |
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| CAS号 | 90176-80-0 | 分子量 | 192.110 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 195.0±40.0 °C at 760 mmHg | |
| 分子式 | C8H4F4O | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 72.1±21.5 °C | |
| 符号 |
GHS02, GHS07 |
信号词 | Warning |
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4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production.
Bioorg. Med. Chem. Lett. 19(5) , 1310-13, (2009) The first examples of thioether-substituted benzonitriles as potential soft-drug androgen receptor antagonists are reported. A number of 4-(alkylthio)- and of 4-(arylthio)-benzonitrile analogs were evaluated in human androgen receptor binding and cellular fun... |
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Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.
J. Med. Chem. 46(24) , 5258-70, (2003) The synthesis and preliminary evaluation of a doxorubicin-formaldehyde conjugate tethered to the nonsteroidal antiandrogen, cyanonilutamide (RU 56279), for the treatment of prostate cancer are reported. The relative ability of the targeting group to bind to t... |
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