4-Fluoro-2-(trifluoromethyl)benzaldehyde
4-Fluoro-2-(trifluoromethyl)benzaldehyde structure
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Common Name | 4-Fluoro-2-(trifluoromethyl)benzaldehyde | ||
|---|---|---|---|---|
| CAS Number | 90176-80-0 | Molecular Weight | 192.110 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 195.0±40.0 °C at 760 mmHg | |
| Molecular Formula | C8H4F4O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 72.1±21.5 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Warning | |
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4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production.
Bioorg. Med. Chem. Lett. 19(5) , 1310-13, (2009) The first examples of thioether-substituted benzonitriles as potential soft-drug androgen receptor antagonists are reported. A number of 4-(alkylthio)- and of 4-(arylthio)-benzonitrile analogs were evaluated in human androgen receptor binding and cellular fun... |
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Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.
J. Med. Chem. 46(24) , 5258-70, (2003) The synthesis and preliminary evaluation of a doxorubicin-formaldehyde conjugate tethered to the nonsteroidal antiandrogen, cyanonilutamide (RU 56279), for the treatment of prostate cancer are reported. The relative ability of the targeting group to bind to t... |
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