2,2'-[4-(2-羟基乙氨基)-3-硝基苯亚氨基]二乙醇胺
![2,2'-[4-(2-羟基乙氨基)-3-硝基苯亚氨基]二乙醇胺结构式](https://image.chemsrc.com/caspic/172/33229-34-4.png)
2,2'-[4-(2-羟基乙氨基)-3-硝基苯亚氨基]二乙醇胺结构式
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常用名 | 2,2'-[4-(2-羟基乙氨基)-3-硝基苯亚氨基]二乙醇胺 | 英文名 | 2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol |
|---|---|---|---|---|
| CAS号 | 33229-34-4 | 分子量 | 285.29600 | |
| 密度 | 1.421 g/cm3 | 沸点 | 582.7ºC at 760 mmHg | |
| 分子式 | C12H19N3O5 | 熔点 | 108-111 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Self-Healing Supramolecular Polymers In Action. van Gemert GML, et al.
Macromol. Chem. Phys. 213(2) , 234-42, (2012)
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NTP Toxicology and Carcinogenesis Studies of HC Blue No. 2 [2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl)imino)bis(ethanol)] (CAS No. 33229-34-4) in F344/N Rats and B6C3F 1 Mice (Feed Studies).
Natl. Toxicol. Program Tech. Rep. Ser. 293 , 1-192, (1985) Toxicology and carcinogenesis studies of HC Blue No. 2 (approximately 98% pure), a semipermanent hair dye, were conducted by administering the test chemical in feed for 103 weeks to groups of 50 F344/N rats of each sex and for 104 weeks to groups of 50 B6C3F ... |
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HC Blue No. 2.
IARC Monogr. Eval. Carcinog. Risks Hum. 57 , 143-51, (1993)
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Failure of short-term in vitro mutagenicity tests to predict the animal carcinogenicity of hair dyes.
Food Chem. Toxicol. 25(9) , 703-7, (1987) A number of hair-dye chemicals that have given positive results in various short-term mutagenicity tests have shown no clear evidence of carcinogenicity in animal bioassays. Commercial HC Blue No. 1 and its analogues HC Red No. 3 and HC Blue No. 2 are all mut... |
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Mutagenicity evaluation of HC Blue No. 1 and HC Blue No. 2, I. Effect on the induction of micronuclei in mouse bone marrow cells.
Mutat. Res. 241(2) , 139-44, (1990) Two hair-dye chemicals, HC Blue No. 1 and HC Blue No. 2, were assessed for the ability to produce chromosome breakage and/or spindle malformation in vivo by evaluating the capacity of these compounds to induce micronuclei in polychromatic erythrocytes of mous... |
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Mutagenicity evaluation of HC Blue No. 1 and HC Blue No. 2, II. Effect on the in vitro induction of unscheduled DNA synthesis in rat, mouse, rabbit, hamster, and monkey primary hepatocytes.
Mutat. Res. 241(2) , 145-50, (1990) 2 hair dyes, HC Blue No. 1 and HC Blue No. 2, were evaluated for the in vitro induction of unscheduled DNA synthesis (UDS) in primary hepatocytes of rat, mouse, hamster, rabbit and monkey. NC Blue No. 1, which is identified as a carcinogen by the National Tox... |
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Mutagenicity evaluation of HC Blue No. 1 and HC Blue No. 2. III. Effects in the Salmonella typhimurium/Escherichia coli reversion assay and the mouse lymphoma L5178Y TK+/- forward mutation assay.
Mutat. Res. 241(2) , 151-9, (1990) The hair-dye ingredients, HC Blue No. 1 (HCB1) and HC Blue No. 2 (HCB2), were tested for the induction of bacterial mutation using Salmonella typhimurium strains TA1535, TA1537, TA98 and TA100; and Escherichia coli strains WP2uvrA-. In addition, both dyes wer... |
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Comparative carcinogenicity of two structurally similar phenylenediamine dyes (HC blue no. 1 and HC blue no. 2) in F344/N rats and B6C3F1 mice.
Toxicology 56(2) , 155-65, (1989) Toxicology and carcinogenesis studies of 2 structurally-related p-phenylenediamines, HC Blue No. 1, and HC Blue No. 2 were conducted by administering each chemical in feed for 103 weeks to both sexes of Fischer 344/N rats and B6C3F1 (C57BL/6N x C3H/HEN) mice.... |
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Comparative metabolism and genotoxicity of the structurally similar nitrophenylenediamine dyes, HC Blue 1 and HC Blue 2, in mouse hepatocytes.
Cell Biol. Toxicol. 6(2) , 139-55, (1990) Previous studies indicated that HC Blue 1 induced heptocellular carcinomas in B6C3F1 mice whereas the structurally similar nitroaromatic amine HC Blue 2 did not. In an attempt to elucidate the biochemical mechanisms responsible for their different carcinogeni... |
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Species comparisons regarding comparative metabolism of two structurally similar phenylenediamines (HC Blue 1 and HC Blue 2).
Prog. Clin. Biol. Res. 340D , 305-14, (1990)
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